This article discusses how a better “map” can develop strategic focus and alignment, increasing the potential for results. Program development and evaluation are best done hand in hand. In complex systems, co-construction has huge yield. It promotes accuracy, comprehensiveness, and utility. Grantmakers can provide more than funding; they can identify and use new tools, processes, and resources with multiple stakeholders for effectiveness. Alignment and integration are powerful principles inside and outside organizations as well as across sectors in pursuit of social change.